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North Carolina State and Mississippi State meet in the Week 2 college football schedule in a matchup of teams that went in opposite directions in Week 1 wins over Group of 5 opponents. MSU squeaked by Louisiana Tech, 35-34, on a last-second field goal after giving up 21 unanswered points, while NC State thrashed USF by a score of 45-0. 

Mississippi State hosts the Wolfpack in Starkville, Miss. at 7 p.m. ET on Saturday. NC State is a one-point favorite in the latest NC State vs. Mississippi State odds at Caesars Sportsbook, while the point total sits at 55.5. Before entering any NC State vs. Mississippi State picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 2 of the 2021 season on a 63-45 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Mississippi State vs. NC State. You can head to SportsLine to see its picks. Here are several college football odds for NC State vs. Mississippi State:

  • Mississippi State vs. NC State spread: NC State -1
  • Mississippi State vs. NC State over-under: 55.5 points

What you need to know about Mississippi State

MSU dodged a bullet last Saturday, finishing off the Louisiana Tech Bulldogs 35-34. The victory came about thanks to a strong surge after the third quarter to overcome a 31-14 deficit. MSU's RB Jo'quavious Marks looked sharp as he punched in two rushing touchdowns in addition to snatching one receiving TD.

Mississippi State may be the least balanced team in all of college football as coach Mike Leach leans on the pass more so than any other coach. The Bulldogs averaged just 43.9 rushing yards per game last year, nearly 25 yards fewer than the second-worst team. They also averaged nearly 300 passing yards per game but could only muster a scoring offense (21.4 points per game) that finished 110th among 128 FBS teams.

What you need to know about NC State

NC State's Week 1 win came against a punchless USF team. Mississippi State provides a much different challenge. NC State will attempt to prove that its success under quarterback Devin Leary (17 for 26 for 232 yards passing vs. USF) and running backs Zonovan Knight and Ricky Person Jr. (combined 268 rushing yards) was no fluke

Mississippi State will look to prove that its Week 1 result was an aberration. The Bulldogs have a case, given that they fumbled the ball five times and lost possession each time. But even if MSU's defense is a great deal better than USF's, NC State's offense can give problems to a unit that still has a lot to figure out. 

How to make Mississippi State vs. NC State picks

The model has simulated NC State vs. Mississippi State 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that hits in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins NC State vs. Mississippi State? And which side of the spread hits well over 50 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.